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J Card Fail. 2009 Mar;15(2):83-97. doi: 10.1016/j.cardfail.2009.01.006.

Genetic evaluation of cardiomyopathy--a Heart Failure Society of America practice guideline.

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  • 1Cardiovascular Division, University of Miami Miller School of Medicine, Miami, Florida 33101-5138, USA. rhershberger@med.miami.edu


Substantial progress has been made recently in understanding the genetic basis of cardiomyopathy. Cardiomyopathies with known genetic cause include hypertrophic (HCM), dilated (DCM), restrictive (RCM), arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) and left ventricular noncompaction (LVNC). HCM, DCM, and RCM have been recognized as distinct clinical entities for decades, whereas ARVD/C and LVNC are relative newcomers to the field. Hence the clinical and genetic knowledge for each cardiomyopathy varies, as do the recommendations and strength of evidence.

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