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    J Theor Biol. 2009 Jun 21;258(4):614-22. doi: 10.1016/j.jtbi.2009.02.010. Epub 2009 Feb 24.

    Mutation-selection equilibrium in games with multiple strategies.

    Source

    Program for Evolutionary Dynamics, Department of Mathematics, Harvard University, Cambridge, MA 02138, USA. tibor_antal@harvard.edu

    Abstract

    In evolutionary games the fitness of individuals is not constant but depends on the relative abundance of the various strategies in the population. Here we study general games among n strategies in populations of large but finite size. We explore stochastic evolutionary dynamics under weak selection, but for any mutation rate. We analyze the frequency dependent Moran process in well-mixed populations, but almost identical results are found for the Wright-Fisher and Pairwise Comparison processes. Surprisingly simple conditions specify whether a strategy is more abundant on average than 1/n, or than another strategy, in the mutation-selection equilibrium. We find one condition that holds for low mutation rate and another condition that holds for high mutation rate. A linear combination of these two conditions holds for any mutation rate. Our results allow a complete characterization of nxn games in the limit of weak selection.

    PMID:
    19248791
    [PubMed - indexed for MEDLINE]
    PMCID:
    PMC2684574
    Free PMC Article

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