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Indian Pediatr. 2009 Feb;46(2):172-4.

Thiamine responsive megaloblastic anemia.

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  • 1Institute of Maternal and Child Health, Medical College, Calicut, India.


This report describes a female child with thiamine responsive megaloblastic anemia syndrome (Rogers syndrome), presenting with anemia and diabetes mellitus responding to thiamine. She also had retinitis pigmentosa. The anemia improved and blood sugar was controlled with daily oral thiamine. Previously unreported olfactory abnormalities, as described in Wolfram syndrome, were also present in our patient.

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