Emerg Infect Dis. 2009 Mar;15(3):436-40.

Evaluation of commercially available anti-dengue virus immunoglobulin M tests.

Hunsperger EA, Yoksan S, Buchy P, Nguyen VC, Sekaran SD, Enria DA, Pelegrino JL, Vázquez S, Artsob H, Drebot M, Gubler DJ, Halstead SB, Guzmán MG, Margolis HS, Nathanson CM, Rizzo Lic NR, Bessoff KE, Kliks S, Peeling RW.

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Serology Diagnostics and Viral Pathogenesis Research Section, Centers for Disease Control and Prevention, San Juan, Puerto Rico.

Abstract

Anti-dengue virus immunoglobulin M kits were evaluated. Test sensitivities were 21%-99% and specificities were 77%-98% compared with reference ELISAs. False-positive results were found for patients with malaria or past dengue infections. Three ELISAs showing strong agreement with reference ELISAs will be included in the World Health Organization Bulk Procurement Scheme.

PMID:: 19239758; [PubMed - indexed for MEDLINE]
PMCID: PMC2681117

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