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Bioinformatics. 2009 Apr 15;25(8):1091-3. doi: 10.1093/bioinformatics/btp101. Epub 2009 Feb 23.

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks.

Author information

  • 1INSERM, AVENIR Team, Integrative Cancer Immunology, U872, Paris, France.

Abstract

We have developed ClueGO, an easy to use Cytoscape plug-in that strongly improves biological interpretation of large lists of genes. ClueGO integrates Gene Ontology (GO) terms as well as KEGG/BioCarta pathways and creates a functionally organized GO/pathway term network. It can analyze one or compare two lists of genes and comprehensively visualizes functionally grouped terms. A one-click update option allows ClueGO to automatically download the most recent GO/KEGG release at any time. ClueGO provides an intuitive representation of the analysis results and can be optionally used in conjunction with the GOlorize plug-in.

PMID:
19237447
[PubMed - indexed for MEDLINE]
PMCID:
PMC2666812
Free PMC Article

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