Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Diabetes Care. 2009 May;32(5):804-6. doi: 10.2337/dc08-2111. Epub 2009 Feb 19.

Depressive symptoms and glycemic control in adolescents with type 1 diabetes: mediational role of blood glucose monitoring.

Author information

  • 1Center for Treatment Adherence, Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

Abstract

OBJECTIVE:

To determine whether the association between depressive symptoms and glycemic control is mediated by blood glucose monitoring (BGM).

RESEARCH DESIGN AND METHODS:

A total of 276 adolescents with type 1 diabetes (mean age +/- SD, 15.6 +/- 1.4 years) completed a measure of depressive symptoms. Sociodemographic and family characteristics were obtained from caregivers. BGM frequency and glycemic control were obtained at a clinic visit.

RESULTS:

Separate regression analyses revealed that depressive symptoms were associated with lower BGM frequency (B = -0.03; P = 0.04) and higher A1C (B = 0.03; P = 0.05) and that lower BGM frequency was associated with higher A1C (B = -0.39; P < 0.001). With depressive symptoms and BGM frequency included together, only BGM frequency was associated with A1C and depressive symptoms became nonsignificant (B = 0.02; P = 0.19). The Sobel test was significant (Z = 1.96; P < 0.05) and showed that 38% of the depression-A1C link can be explained by BGM.

CONCLUSIONS:

BGM is a mediator between depressive symptoms and glycemic control in adolescents with type 1 diabetes.

PMID:
19228870
[PubMed - indexed for MEDLINE]
PMCID:
PMC2671131
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Write to the Help Desk