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Genome Biol. 2009 Feb 2;10(2):207. doi: 10.1186/gb-2009-10-2-207.

Protein function annotation by homology-based inference.

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  • 1Department of Biological Chemistry, The Hebrew University of Jerusalem, Sudarsky Center, Jerusalem 91904, Israel.

Abstract

With many genomes now sequenced, computational annotation methods to characterize genes and proteins from their sequence are increasingly important. The BioSapiens Network has developed tools to address all stages of this process, and here we review progress in the automated prediction of protein function based on protein sequence and structure.

PMID:
19226439
[PubMed - indexed for MEDLINE]
PMCID:
PMC2688287
Free PMC Article
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