Synthesis of the pyrrolo[2,3-c]carbazole core of the dictyodendrins

Carles Ayats; Roger Soley; Fernando Albericio; Mercedes Alvarez

doi:10.1039/b822933n

Synthesis of the pyrrolo[2,3-c]carbazole core of the dictyodendrins

Org Biomol Chem. 2009 Mar 7;7(5):860-2. doi: 10.1039/b822933n. Epub 2009 Jan 13.

Authors

Carles Ayats¹, Roger Soley, Fernando Albericio, Mercedes Alvarez

Affiliation

¹ Institute for Research in Biomedicine, Barcelona Scientific Park-University of Barcelona, Baldiri Reixach 10-12, E-08028 Barcelona, Spain.

PMID: 19225666
DOI: 10.1039/b822933n

Abstract

The pyrrolo[2,3-c]carbazole , the common core of the marine alkaloids known as the dictyodendrins, has been synthesised. The sequence is based on a Suzuki cross-coupling reaction between the pyrrole fragment and the indole fragment , followed by tandem photochemical 6pi-electrocyclization/aromatisation.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alkaloids
Carbazoles / chemical synthesis*
Indoles / chemistry
Marine Biology
Photochemistry
Pyrroles / chemical synthesis*
Pyrroles / chemistry

Substances

Alkaloids
Carbazoles
Indoles
Pyrroles
dictyodendrin B
dictyodendrin C
dictyodendrin E