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    Curr Opin Cell Biol. 2009 Feb;21(1):97-108. Epub 2009 Feb 14.

    The structural dynamics of macromolecular processes.

    Russel D, Lasker K, Phillips J, Schneidman-Duhovny D, Velázquez-Muriel JA, Sali A.

    Department of Bioengineering and Therapeutic Sciences, University of California at San Francisco, 1700 4th Street, San Francisco, CA 94158-2330, USA.

    Dynamic processes involving macromolecular complexes are essential to cell function. These processes take place over a wide variety of length scales from nanometers to micrometers, and over time scales from nanoseconds to minutes. As a result, information from a variety of different experimental and computational approaches is required. We review the relevant sources of information and introduce a framework for integrating the data to produce representations of dynamic processes.

    PMID: 19223165 [PubMed - indexed for MEDLINE]

    PMCID: 2774249

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