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Curr Opin Cell Biol. 2009 Feb;21(1):97-108. doi: 10.1016/j.ceb.2009.01.022. Epub 2009 Feb 14.

The structural dynamics of macromolecular processes.

Author information

  • 1Department of Bioengineering and Therapeutic Sciences, University of California at San Francisco, 1700 4th Street, San Francisco, CA 94158-2330, USA.

Abstract

Dynamic processes involving macromolecular complexes are essential to cell function. These processes take place over a wide variety of length scales from nanometers to micrometers, and over time scales from nanoseconds to minutes. As a result, information from a variety of different experimental and computational approaches is required. We review the relevant sources of information and introduce a framework for integrating the data to produce representations of dynamic processes.

PMID:
19223165
[PubMed - indexed for MEDLINE]
PMCID:
PMC2774249
Free PMC Article

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