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Trends Parasitol. 2009 Mar;25(3):124-31. doi: 10.1016/j.pt.2008.12.007. Epub 2009 Feb 13.

Using differential gene expression to study Entamoeba histolytica pathogenesis.

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  • 1Division of Infectious Diseases and International Health, Departments of Medicine, Microbiology and Pathology, University of Virginia, PO Box 801340, Charlottesville, VA 22908-1340, USA.


The release of the Entamoeba histolytica genome has facilitated the development of techniques to survey rapidly and to relate gene expression with biology. The association and potential contribution of differential gene expression to the life cycle and the virulence of this protozoan parasite of humans are reviewed here.

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