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Zhejiang Food and Drug Administration, Hangzhou 310012, Zhejiang Province, PR China. yunzhoucn@yahoo.com.cn
Three new saponins, bacopasides IX-XI (1- 3), together with their known analogues bacopaside I (4), bacopaside II (5), bacopasaponsin C (6), and bacopasaponsin D (7), were isolated from the whole plant of Bacopa monniera. Compounds 3, 4, and 6 showed nootropic activity when tested in the Morris water maze test and step-down test of scopolamine-induced memory impairment in mice.
Copyright Georg Thieme Verlag KG Stuttgart. New York.
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