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Ren Fail. 2009;31(2):144-8. doi: 10.1080/08860220802595518.

Kikuchi-Fujimoto disease and systemic lupus erythematosus: the EBV connection?

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  • 1Department of Nephrology, General Hospital G. Papanikolaou, Thessaloniki, Greece. lgionanlis@yahoo.com


Kikuchi-Fujimoto disease (KFD) is a benign and self-limited disease of unknown etiology that affects mainly young women. It presents with localized lymphadenopathy, usually cervical, accompanied with fever, night sweats, and leucopenia. KFD has been rarely described in association with autoimmune disorders, mainly systemic lupus erythematosus (SLE). We report the case of a young patient presenting with KFD coinciding with SLE. The association of KFD and SLE is reviewed. Moreover, a possible pathogenetic role of Ebstein-Barr virus linking the two clinical entities is discussed.

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