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J Rheumatol. 1991 Jul;18(7):1091-4.

Intraarticular corticosteroids possibly leading to local osteonecrosis and marrow fat induced synovitis.

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  • 1Department of Medicine, Medical College of Wisconsin, Milwaukee 53226.

Abstract

We describe a woman with recurrent synovitis in one or both knees treated with intraarticular corticosteroid injections and two 6-day courses of methylprednisolone tablets. She later developed osteonecrosis of her distal femora and proximal tibiae. Her course was complicated by persistent synovitis associated with a large quantity of necrotic fat in the joint fluid.

PMID:
1920314
[PubMed - indexed for MEDLINE]
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