J Nat Prod. 1991 Mar-Apr;54(2):453-9.

Plant metabolites. New compounds and anti-inflammatory activity of Uncaria tomentosa.

Aquino R, De Feo V, De Simone F, Pizza C, Cirino G.

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Dipartimento di Chimica delle Sostanze Naturali, Università degli Studi di Napoli Federico II, Italy.

Abstract

Bioassay-directed fractionation of the anti-inflammatory extracts of Uncaria tomentosa, using the carrageenan-induced edema in rat paw, has led to the isolation of a new quinovic acid glycoside 7 as one of the active principles. Furthermore, a new triterpene 8 was isolated as its methyl ester. The structures were elucidated by spectral and chemical studies.

PMID:: 1919590; [PubMed - indexed for MEDLINE]

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