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Eur J Obstet Gynecol Reprod Biol. 2009 Apr;143(2):93-7. doi: 10.1016/j.ejogrb.2008.12.013. Epub 2009 Feb 4.

Feasibility and morbidity of using saline filled tissue expanders to reduce radiation-induced bowel injury in patients with gynecologic malignancies.

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  • 1Division of Gynecologic Oncology, University of Minnesota, Department of Obstetrics, Gynecology and Women's Health, Minneapolis, MN 55455, USA. gelle005@umn.edu

Abstract

OBJECTIVES:

To evaluate the feasibility and morbidity of using saline filled tissue expanders (TE) to displace the small bowel during radiation therapy in patients with gynecologic malignancies.

STUDY DESIGN:

Ten patients undergoing surgical exploration for a gynecologic malignancy and deemed to be at high risk for the late effects of radiation therapy were consented for the possible placement of a TE. Indication for placement was need for post-operative radiation. Small bowel exclusion was reported in terms of the lowest loop identified on treatment planning film using orally ingested barium.

RESULTS:

Small bowel loops were excluded from the pelvis to varying degrees in all patients. Lowest identifiable bowel was marked at the L4-L5 interspace in one patient, L5-S1 interspace in three patients, at or near the sacral promontory in three patients, and to the middle of S2 in one patient. In two patients the TE was removed prior to simulation. Early complications included migration of the TE during treatment, development of a vesicovaginal fistula requiring immediate removal of the TE, and enterocutaneous fistula formation in a patient who developed an abscess following treatment completion. Another patient experienced a rectovaginal fistula 18 months after removal of the TE.

CONCLUSIONS:

TE placement can successfully isolate small bowel from the pelvis. Usage should be individualized to minimize the likelihood of short and long-term complications, particularly in patients at higher risk of morbidity.

PMID:
19195764
[PubMed - indexed for MEDLINE]
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