J Pediatr Hematol Oncol. 2009 Feb;31(2):145-7.

Long-term disease control of refractory anaplastic large cell lymphoma with vinblastine.

Garner R, Li Y, Gray B, Zori R, Braylan R, Wall J, Hunger SP.

Source

Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, USA.

Abstract

Anaplastic large cell lymphoma (ALCL) is a unique clinical and pathologic subtype of lymphoma characterized by the proliferation of large, highly pleomorphic CD30-positive cells. Overall 70% to 80% of children with ALCL are cured with modern chemotherapy regimens, but the disease is often resistant to multiple therapies after relapse. Single agent vinblastine therapy has been effective in some cases of refractory ALCL. We report a case of ALCL originally diagnosed in an 8-year-old girl. After relapse, the disease was refractory to multiagent chemotherapy, but has showed remarkable response to, and dependence on, single agent vinblastine treatment for almost 7 years.

PMID:: 19194204; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Case Reports

MeSH Terms

Substances

Vinblastine

LinkOut - more resources

Full Text Sources

Supplemental Content

Save items

Related citations in PubMed

Single-drug vinblastine as salvage treatment for refractory or relapsed anaplastic large-cell lymphoma: a report from the French Society of Pediatric Oncology. [J Clin Oncol. 2009]
Single-drug vinblastine as salvage treatment for refractory or relapsed anaplastic large-cell lymphoma: a report from the French Society of Pediatric Oncology.
Brugières L, Pacquement H, Le Deley MC, Leverger G, Lutz P, Paillard C, Baruchel A, Frappaz D, Nelken B, Lamant L, et al. J Clin Oncol. 2009 Oct 20; 27(30):5056-61. Epub 2009 Sep 8.
Long-term remission of children with relapsed and secondary anaplastic large cell non-Hodgkin lymphoma (ALCL) following treatment with pulsed dexamethasone and low dose etoposide. [Pediatr Blood Cancer. 2008]
Long-term remission of children with relapsed and secondary anaplastic large cell non-Hodgkin lymphoma (ALCL) following treatment with pulsed dexamethasone and low dose etoposide.
Stockklausner C, Behnisch W, Mechtersheimer G, Möller P, Kulozik AE. Pediatr Blood Cancer. 2008 Jan; 50(1):126-9.
Trofosfamide as salvage therapy for anaplastic large cell lymphoma relapsing after high-dose chemotherapy. [Leuk Lymphoma. 2002]
Trofosfamide as salvage therapy for anaplastic large cell lymphoma relapsing after high-dose chemotherapy.
Andersson PO, Braide I, Nilsson-Ehle H. Leuk Lymphoma. 2002 Dec; 43(12):2351-3.
Review Management of multifocal primary cutaneous CD30 anaplastic large cell lymphoma. [J Am Acad Dermatol. 2004]
Review Management of multifocal primary cutaneous CD30 anaplastic large cell lymphoma.
Shehan JM, Kalaaji AN, Markovic SN, Ahmed I. J Am Acad Dermatol. 2004 Jul; 51(1):103-10.
Review Primary cutaneous Ki-1(CD30) positive anaplastic large cell lymphoma in childhood. [J Am Acad Dermatol. 1999]
Review Primary cutaneous Ki-1(CD30) positive anaplastic large cell lymphoma in childhood.
Tomaszewski MM, Moad JC, Lupton GP. J Am Acad Dermatol. 1999 May; 40(5 Pt 2):857-61.

See reviews... See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.

Recent activity

Clear Turn Off Turn On

Long-term disease control of refractory anaplastic large cell lymphoma with vinb...
Long-term disease control of refractory anaplastic large cell lymphoma with vinblastine.
J Pediatr Hematol Oncol. 2009 Feb ;31(2):145-7.

PubMed
Glutamate, microdialysis, and cerebral ischemia: lost in translation?
Glutamate, microdialysis, and cerebral ischemia: lost in translation?
Anesthesiology. 2009 Feb ;110(2):422-5.

PubMed
Perioperative glycemic control: an evidence-based review.
Perioperative glycemic control: an evidence-based review.
Anesthesiology. 2009 Feb ;110(2):408-21.

PubMed
Leg design in hexapedal runners.
Leg design in hexapedal runners.
J Exp Biol. 1991 Jul ;158:369-90.

PubMed
Omission of day 2 of antiemetic medications is a cost saving strategy for improv...
Omission of day 2 of antiemetic medications is a cost saving strategy for improving chemotherapy-induced nausea and vomiting control: results of a randomized phase III trial.
Am J Clin Oncol. 2009 Feb ;32(1):23-6.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Long-term disease control of refractory anaplastic large cell lymphoma with vinblastine.

Source

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Molecular Biology Databases

Supplemental Content

Save items

Related citations in PubMed

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information