Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Indian J Pediatr. 2008 Dec;75(12):1223-5. doi: 10.1007/s12098-008-0242-z. Epub 2009 Feb 4.

Cardiac enzyme levels in myocardial dysfunction in newborns with perinatal asphyxia.

Author information

  • 1Department of Paediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

Abstract

OBJECTIVE:

To study the usefulness of cardiac enzymes in evaluating myocardial damage in perinatal asphyxia.

METHODS:

Thirty term babies with perinatal asphyxia and without any congenital malformations were selected as cases. They were compared with thirty healthy term babies without asphyxia. Myocardial dysfunction was evaluated using clinical, electrocardiography, echocardiography and cardiac enzymes i.e, troponin-T and CK-MB levels.

RESULTS:

Among the 30 cases 23 had evidence of myocardial involvement while one baby in the control group had ECG evidence compatible with cardiac involvement. Cardiac enzymes were significantly increased in babies with perinatal asphyxia. The mean level of C-troponin-T among cases and controls were 0.22+/-0.28 and 0.003+/-0.018 while CK-MB levels were 121+/-77.4 IU/L and 28.8 +/- 20.2 IU/L respectively. C-troponin-T had higher sensitivity and specificity compared to CK-MB levels. Moreover, C troponin-T levels correlated well with severity and outcome in babies with perinatal asphyxia.

CONCLUSION:

C-Tropopnin assay is useful in evaluating the severity of myocardial damage and outcome in perinatal asphyxia.

PMID:
19190877
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Springer
    Loading ...
    Write to the Help Desk