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Integr Cancer Ther. 2009 Mar;8(1):37-46. doi: 10.1177/1534735409331456. Epub 2009 Feb 3.

Effects of a yoga program on cortisol rhythm and mood states in early breast cancer patients undergoing adjuvant radiotherapy: a randomized controlled trial.

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  • 1Department of Yoga Research, Swami Vivekananda Yoga Anusandhana Samsthana, Bangalore, India [corrected]

Erratum in

  • Integr Cancer Ther. 2009 Jun;8(2):195.

Abstract

Objectives. This study compares the effects of an integrated yoga program with brief supportive therapy in breast cancer outpatients undergoing adjuvant radiotherapy at a cancer center.

METHODS:

Eighty-eight stage II and III breast cancer outpatients are randomly assigned to receive yoga (n = 44) or brief supportive therapy (n = 44) prior to radiotherapy treatment. Assessments include diurnal salivary cortisol levels 3 days before and after radiotherapy and self-ratings of anxiety, depression, and stress collected before and after 6 weeks of radiotherapy.

RESULTS:

Analysis of covariance reveals significant decreases in anxiety (P < .001), depression (P = .002), perceived stress (P < .001), 6 a.m. salivary cortisol (P = .009), and pooled mean cortisol (P = .03) in the yoga group compared with controls. There is a significant positive correlation between morning salivary cortisol level and anxiety and depression.

CONCLUSION:

Yoga might have a role in managing self-reported psychological distress and modulating circadian patterns of stress hormones in early breast cancer patients undergoing adjuvant radiotherapy.

PMID:
19190034
[PubMed - indexed for MEDLINE]
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