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J Pediatr Endocrinol Metab. 2008 Dec;21(12):1191-4.

Recurrent acute pancreatitis in a child with primary hyperparathyroidism.

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  • 1Departments of Pediatric Gastroenterology, Nutrition, and Hepatology, Yale University School of Medicine, New Haven, CT 06520, USA.


Hypercalcemia is an important etiology to consider in the evaluation of acute pancreatitis. Not only is it a treatable cause, but understanding the basis for this etiology may provide new insight into the common biochemical mechanisms involved in the pathogenesis of pancreatitis. We report a case of an 11-year-old girl with hypercalcemia due to primary hyperparathyroidism who developed recurrent pancreatitis. We review clinical and experimental data that implicate hypercalcemia as the cause and discuss mechanisms for the association.

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