Bioinformatics. 2009 Mar 15;25(6):830-1. Epub 2009 Jan 28.

The DICS repository: module-assisted analysis of disease-related gene lists.

Dietmann S, Georgii E, Antonov A, Tsuda K, Mewes HW.

Source

Institute for Bioinformatics and Systems Biology, German Research Center for Environmental Health, Ingolstädter Landstrasse 1, D-85764 Neuherberg, Germany. sabine.dietmann@googlemail.com

Abstract

SUMMARY: The DICS database is a dynamic web repository of computationally predicted functional modules from the human protein-protein interaction network. It provides references to the CORUM, DrugBank, KEGG and Reactome pathway databases. DICS can be accessed for retrieving sets of overlapping modules and protein complexes that are significantly enriched in a gene list, thereby providing valuable information about the functional context. AVAILABILITY: Supplementary information on datasets and methods is available on the web server http://mips.gsf.de/proj/dics.

PMID:: 19176557; [PubMed - indexed for MEDLINE]

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