J Mol Neurosci. 2009 Sep;39(1-2):1-8. Epub 2009 Jan 23.

Neuroprotective protein and carboxypeptidase E.

Koshimizu H, Senatorov V, Loh YP, Gozes I.

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Section on Cellular Neurobiology, Program on Developmental Neuroscience, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

Abstract

This review outlines the neuroprotective activities and structural specificities of two distinct proteins, activity-dependent neuroprotective protein, a protein assigned transcription factor/chromatin remodeling activity, and carboxypeptidase E, a classic exopeptidase. Future studies will elucidate how these two versatile proteins converge onto a similar endpoint: neuroprotection.

PMID:: 19165633; [PubMed - indexed for MEDLINE]

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Neuroprotective protein and carboxypeptidase E.

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