On the synthesis of multiple frequency tone burst stimuli for efficient high frequency auditory brainstem response

Annu Int Conf IEEE Eng Med Biol Soc. 2008:2008:4158-61. doi: 10.1109/IEMBS.2008.4650125.

Abstract

The development and digital waveform synthesis of a multiple-frequency tone-burst (MFTB) stimulus is presented. The stimulus is designed to improve the efficiency of monitoring high-frequency auditory-brainstem-response (ABR) hearing thresholds. The pure-tone-based, fractional-octave-bandwidth MFTB supports frequency selective ABR audiometry with a bandwidth that falls between the conventional click and single-frequency tone-burst stimuli. The MFTB is being used to identify high frequency hearing threshold change due to ototoxic medication which most generally starts at the ultra-highest hearing frequencies and progresses downwards but could be useful in general limited-bandwidth testing applications. Included is a Mathcad implementation and analysis of our MFTB synthesis technique and sample performance measurements of the MFTB stimulus configuration used in a clinical research ABR system.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Algorithms
  • Audiometry, Evoked Response / methods*
  • Audiometry, Pure-Tone / methods*
  • Auditory Threshold / physiology*
  • Calibration
  • Computers
  • Electronic Data Processing
  • Equipment Design
  • Evoked Potentials, Auditory, Brain Stem / physiology*
  • Humans
  • Models, Statistical
  • Predictive Value of Tests
  • Reproducibility of Results
  • Software
  • Time Factors