Trends Microbiol. 2009 Feb;17(2):47-53. Epub 2009 Jan 21.

Genomic islands are dynamic, ancient integrative elements in bacterial evolution.

Source

Department of Biological Sciences, University of Delaware, Newark, DE 19716, USA. fboyd@udel.edu

Abstract

Acquisition of genomic islands plays a central part in bacterial evolution as a mechanism of diversification and adaptation. Genomic islands are non-self-mobilizing integrative and excisive elements that encode diverse functional characteristics but all contain a recombination module comprised of an integrase, associated attachment sites and, in some cases, a recombination directionality factor. Here, we discuss how a group of related genomic islands are evolutionarily ancient elements unrelated to plasmids, phages, integrons and integrative conjugative elements. In addition, we explore the diversity of genomic islands and their insertion sites among Gram-negative bacteria and discuss why they integrate at a limited number of tRNA genes.

PMID:: 19162481; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Supplemental Content

Related citations

Genomic island excisions in Bordetella petrii. [BMC Microbiol. 2009]
Genomic island excisions in Bordetella petrii.
Lechner M, Schmitt K, Bauer S, Hot D, Hubans C, Levillain E, Locht C, Lemoine Y, Gross R. BMC Microbiol. 2009 Jul 18; 9:141. Epub 2009 Jul 18.
Dichotomy in the evolution of pathogenicity island and bacteriophage encoded integrases from pathogenic Escherichia coli strains. [Infect Genet Evol. 2011]
Dichotomy in the evolution of pathogenicity island and bacteriophage encoded integrases from pathogenic Escherichia coli strains.
Napolitano MG, Almagro-Moreno S, Boyd EF. Infect Genet Evol. 2011 Mar; 11(2):423-36. Epub 2010 Dec 13.
Review The Yersinia high-pathogenicity island (HPI): evolutionary and functional aspects. [Int J Med Microbiol. 2004]
Review The Yersinia high-pathogenicity island (HPI): evolutionary and functional aspects.
Schubert S, Rakin A, Heesemann J. Int J Med Microbiol. 2004 Sep; 294(2-3):83-94.
Excision and transfer of the Mesorhizobium loti R7A symbiosis island requires an integrase IntS, a novel recombination directionality factor RdfS, and a putative relaxase RlxS. [Mol Microbiol. 2006]
Excision and transfer of the Mesorhizobium loti R7A symbiosis island requires an integrase IntS, a novel recombination directionality factor RdfS, and a putative relaxase RlxS.
Ramsay JP, Sullivan JT, Stuart GS, Lamont IL, Ronson CW. Mol Microbiol. 2006 Nov; 62(3):723-34.
Review [Bacterial genomic islands: organization, function, and role in evolution]. [Mol Biol (Mosk). 2002]
Review [Bacterial genomic islands: organization, function, and role in evolution].
Il'ina TS, Romanova IuM. Mol Biol (Mosk). 2002 Mar-Apr; 36(2):228-39.

See reviews... See all...

Cited by 13 PubMed Central articles

A Rickettsia genome overrun by mobile genetic elements provides insight into the acquisition of genes characteristic of an obligate intracellular lifestyle. [J Bacteriol. 2012]
A Rickettsia genome overrun by mobile genetic elements provides insight into the acquisition of genes characteristic of an obligate intracellular lifestyle.
Gillespie JJ, Joardar V, Williams KP, Driscoll T, Hostetler JB, Nordberg E, Shukla M, Walenz B, Hill CA, Nene VM, et al. J Bacteriol. 2012 Jan; 194(2):376-94. Epub 2011 Nov 4.
ICEberg: a web-based resource for integrative and conjugative elements found in Bacteria. [Nucleic Acids Res. 2012]
ICEberg: a web-based resource for integrative and conjugative elements found in Bacteria.
Bi D, Xu Z, Harrison EM, Tai C, Wei Y, He X, Jia S, Deng Z, Rajakumar K, Ou HY. Nucleic Acids Res. 2012 Jan; 40(Database issue):D621-6. Epub 2011 Oct 18.
Antimicrobial resistance and virulence determinants in European Salmonella genomic island 1-positive Salmonella enterica isolates from different origins. [Appl Environ Microbiol. 2011]
Antimicrobial resistance and virulence determinants in European Salmonella genomic island 1-positive Salmonella enterica isolates from different origins.
Beutlich J, Jahn S, Malorny B, Hauser E, Hühn S, Schroeter A, Rodicio MR, Appel B, Threlfall J, Mevius D, et al. Appl Environ Microbiol. 2011 Aug 15; 77(16):5655-64. Epub 2011 Jun 24.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

Genomic islands are dynamic, ancient integrative elements in bacterial evolution...
Genomic islands are dynamic, ancient integrative elements in bacterial evolution.
Trends Microbiol. 2009 Feb ;17(2):47-53. Epub 2009 Jan 21 .

PubMed
Boswellia sacra essential oil induces tumor cell-specific apoptosis and suppress...
Boswellia sacra essential oil induces tumor cell-specific apoptosis and suppresses tumor aggressiveness in cultured human breast cancer cells.
BMC Complement Altern Med. 2011 Dec 15 ;11:129.

PubMed
Role of temozolomide after radiotherapy for newly diagnosed diffuse brainstem gl...
Role of temozolomide after radiotherapy for newly diagnosed diffuse brainstem glioma in children: results of a multiinstitutional study (SJHG-98).
Cancer. 2005 Jan 1 ;103(1):133-9.

PubMed
Genome-wide association study of intracranial aneurysm identifies three new risk...
Genome-wide association study of intracranial aneurysm identifies three new risk loci.
Nat Genet. 2010 May ;42(5):420-5. Epub 2010 Apr 4 .

PubMed
Actinobacteria as mutualists: general healthcare for insects?
Actinobacteria as mutualists: general healthcare for insects?
Trends Microbiol. 2009 Dec ;17(12):529-35. Epub 2009 Oct 21 .

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to: