EMBO J. 2009 Jan 21;28(2):84-5.

Circadian clocks can take a few transcriptional knocks.

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Centre for Systems Biology at Edinburgh, The University of Edinburgh, Biological Sciences, Edinburgh, UK. john.oneill@ed.ac.uk

Abstract

A thought-provoking study in this issue of The EMBO Journal shows that the circadian clock in mouse fibroblasts is surprisingly insensitive to the inhibition of total cellular mRNA production. The authors go on to show intriguing parallels between compensation of period to changes in temperature and global transcription rate.

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EMBO J. 2009 Jan 21;28(2):123-34.

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