Pregnancy in true hermaphrodites and all male offspring to date

Obstet Gynecol. 2009 Feb;113(2 Pt 2):534-536. doi: 10.1097/AOG.0b013e3181866456.

Abstract

Background: There are 11 reported cases of pregnancy in true hermaphrodites, but none with advanced genetic testing. All known fetuses have been male.

Case: A true hermaphrodite with a spontaneous pregnancy prenatally known to have a remaining portion of a right ovotestis, delivered a male neonate. The mother has a 46, XX karyotype with polymerase chain reaction demonstrating low levels of the Yq12 sequence. Postpartum androgen levels were normal.

Conclusion: Partial removal of testicular tissue may enhance fertility in hermaphrodites, and there may be a genetic basis for the progeny to be male.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Amniocentesis
  • Female
  • Humans
  • Hydronephrosis
  • Infant, Newborn
  • Male
  • Oligohydramnios
  • Ovary / ultrastructure*
  • Ovotesticular Disorders of Sex Development / genetics*
  • Pregnancy
  • Sex Determination Analysis*
  • Term Birth
  • Testis / ultrastructure*