Format

Send to:

Choose Destination
See comment in PubMed Commons below
Cell Host Microbe. 2009 Jan 22;5(1):6-7. doi: 10.1016/j.chom.2008.12.005.

Cholesterol paves the way for topically applied viricides.

Author information

  • 1Department of Molecular Biology, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA. jrossi@coh.org

Abstract

Sexually transmitted viral infections have the potential to be prevented and treated by topical viricides. Here, Wu et al. (2009) demonstrate that cholesterol-conjugated small interfering RNAs (siRNAs) targeting a cellular receptor combined with an antiviral siRNA when topically applied to mucosal tissue blocked lethal herpes virus infections in mice.

PMID:
19154982
[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk