Eur Spine J. 2009 Apr;18(4):449-64. Epub 2009 Jan 17.

Bone graft substitutes in anterior cervical discectomy and fusion.

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University of New South Wales, Sydney, Australia.

Abstract

Anterior cervical discectomy with fusion is a common surgical procedure for patients suffering pain and/or neurological deficits and unresponsive to conservative management. For decades, autologous bone grafted from the iliac crest has been used as a substrate for cervical arthrodesis. However patient dissatisfaction with donor site morbidity has led to the search for alternative techniques. We present a literature review examining the progress of available grafting options as assessed in human clinical trials, considering allograft-based, synthetic, factor- and cell-based technologies.

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PMCID:: PMC2899466

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Bone graft substitutes in anterior cervical discectomy and fusion.

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