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Strategies for inhibiting function of HIV-1 accessory proteins: a necessary route to AIDS therapy?

Richter SN, Frasson I, Pal├╣ G.

Curr Med Chem. 2009;16(3):267-86. Review.


HIV-1 Nef assembles a Src family kinase-ZAP-70/Syk-PI3K cascade to downregulate cell-surface MHC-I.

Hung CH, Thomas L, Ruby CE, Atkins KM, Morris NP, Knight ZA, Scholz I, Barklis E, Weinberg AD, Shokat KM, Thomas G.

Cell Host Microbe. 2007 Apr 19;1(2):121-33.


HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes.

Piguet V, Wan L, Borel C, Mangasarian A, Demaurex N, Thomas G, Trono D.

Nat Cell Biol. 2000 Mar;2(3):163-7.

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