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Clin Med. 2008 Dec;8(6):579-88.

De Testimonio: on the evidence for decisions about the use of therapeutic interventions.

Author information

  • National Institute for Health and Clinical Excellence, London. Michael.rawlins@nice.org.uk


Decisions about the use of therapeutic interventions, whether for individuals or entire healthcare systems, should be based on the totality of the available evidence. The notion that evidence can be reliably or usefully placed in 'hierarchies' is illusory. Rather, decision makers need to exercise judgement about whether (and when) evidence gathered from experimental or observational sources is fit for purpose.

Comment in

  • Harveian Oration 2008. [Clin Med. 2009]
[PubMed - indexed for MEDLINE]
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