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Immunity. 2009 Jan 16;30(1):1-2. doi: 10.1016/j.immuni.2008.12.011.

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  • Cancer Sciences Division, School of Medicine, University of Southampton, Southampton, UK.


In this issue of Immunity, Dong et al. (2009) describe the protein crystal structure heterodimer of tapasin and ERp57, which helps visualize the function of these proteins in loading of peptide antigens onto MHC class I molecules as part of the peptide loading complex within the endoplasmic reticulum.

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