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Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1313-7. doi: 10.1073/pnas.0812068106. Epub 2009 Jan 12.

Nanoscale magnetic resonance imaging.

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  • 1IBM Research Division, Almaden Research Center, 650 Harry Road, San Jose, CA 95120, USA.

Abstract

We have combined ultrasensitive magnetic resonance force microscopy (MRFM) with 3D image reconstruction to achieve magnetic resonance imaging (MRI) with resolution <10 nm. The image reconstruction converts measured magnetic force data into a 3D map of nuclear spin density, taking advantage of the unique characteristics of the "resonant slice" that is projected outward from a nanoscale magnetic tip. The basic principles are demonstrated by imaging the (1)H spin density within individual tobacco mosaic virus particles sitting on a nanometer-thick layer of adsorbed hydrocarbons. This result, which represents a 100 million-fold improvement in volume resolution over conventional MRI, demonstrates the potential of MRFM as a tool for 3D, elementally selective imaging on the nanometer scale.

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PMID:
19139397
[PubMed - indexed for MEDLINE]
PMCID:
PMC2628306
Free PMC Article

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