Indian J Pathol Microbiol. 2009 Jan-Mar;52(1):94-6.

Bilateral benign non functional struma ovarii with Pseudo-Meigs' syndrome.

Rana V, Srinivas V, Bandyopadhyay S, Ghosh SK, Singh Y.

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Department of Pathology, Command Hospital (EC) Alipore, Kolkata 700 027, India. yashvandana@gmail.com

Abstract

Bilateral presentation of benign Struma ovarii is rare and has not been reported frequently in published literature. A 70-year-old postmenopausal female presented with progressive ascites, bilateral pleural effusion and elevated CA-125 levels. The contrast-enhanced computed tomography (CECT) of the abdomen and pelvis revealed a heterogenous mass in the left adnexa. These findings were suspicious for an ovarian malignancy. After surgery the diagnosis of non functional, bilateral benign Struma ovarii was made. Struma ovarii is a specialized ovarian teratoma composed predominantly of mature thyroid tissue. It is associated with pleural effusion and ascites (Pseudo-Meigs' syndrome) in 5% of cases. The combination of struma ovarii and elevated CA-125 levels has been reported infrequently. This is a rare case of bilateral benign struma ovarii associated with Pseudo-Meigs' syndrome and elevated CA-125 levels. Surgical excision of the ovarian masses induced immediate resolution of the ascites and pleural effusion and a reduction of the serum CA-125 level.

PMID:: 19136795; [PubMed - indexed for MEDLINE]

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CA-125 Antigen

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Cited by 2 PubMed Central articles

Struma ovarii associated with Pseudo-Meig's syndrome and high serum level of CA 125; a case report. [J Ovarian Res. 2012]
Struma ovarii associated with Pseudo-Meig's syndrome and high serum level of CA 125; a case report.
Mostaghel N, Enzevaei A, Zare K, Fallahian M. J Ovarian Res. 2012 Mar 21; 5:10. Epub 2012 Mar 21.
Struma ovarii associated with pseudo-Meigs' syndrome and elevated serum CA 125: a case report and review of the literature. [J Ovarian Res. 2010]
Struma ovarii associated with pseudo-Meigs' syndrome and elevated serum CA 125: a case report and review of the literature.
Jiang W, Lu X, Zhu ZL, Liu XS, Xu CJ. J Ovarian Res. 2010 Jul 29; 3:18. Epub 2010 Jul 29.

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