Send to:

Choose Destination
See comment in PubMed Commons below
Infect Dis Clin North Am. 2009 Mar;23(1):73-98. doi: 10.1016/j.idc.2008.10.001.

Coagulase-negative staphylococcal infections.

Author information

  • 1Department of Pathology and Microbiology, University of Nebraska Medical Center, 986280 Nebraska Medical Center, Omaha, NE 68198-6280, USA.


Coagulase-negative staphylococci (CNS) are differentiated from the closely related but more virulent Staphylococcus aureus by their inability to produce free coagulase. Currently, there are over 40 recognized species of CNS. These organisms typically reside on healthy human skin and mucus membranes, rarely cause disease, and are most frequently encountered by clinicians as contaminants of microbiological cultures. However, CNS have been increasingly recognized to cause clinically significant infections. The conversion of the CNS from symbiont to human pathogen has been a direct reflection of the use of indwelling medical devices. This article deals with the clinical syndromes, epidemiology, prevention, and management of infections caused by this unique group of organisms.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk