Neuro-endocrine cells--a new prognostic parameter ...[Br J Urol. 1991]

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1: Br J Urol. 1991 Sep;68(3):258-62.Links

Neuro-endocrine cells--a new prognostic parameter in prostate cancer.

Cohen RJ, Glezerson G, Haffejee Z.

Department of Anatomical Pathology, University of the Witwatersrand, Johannesburg, South Africa.

Neuro-endocrine cells are a recognised component of prostatic ducts and acini. Half of all clinically manifest cancers show neuro-endocrine differentiation. Occult carcinomas have a lower incidence of such differentiation. Neuro-endocrine cells are of major prognostic importance and appear more reliable in predicting patients' survival than do conventional histological grading systems.

PMID: 1913066 [PubMed - indexed for MEDLINE]

Prostatic carcinoma: histological and immunohistological factors affecting prognosis. [Br J Urol. 1990]
Endocrine-paracrine cell types in the prostate and prostatic adenocarcinoma are postmitotic cells. [Hum Pathol. 1995]
Neuroendocrine cells of the prostate and neuroendocrine differentiation in prostatic carcinoma: a review of morphologic aspects. [Urology. 1998]
Prognostic significance of neuroendocrine differentiation, proliferation activity and androgen receptor expression in prostate cancer. [Pathol Int. 2001]
Are neuroendocrine cells of practical value as an independent prognostic parameter in prostate cancer? [Br J Urol. 1995]
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Neuro-endocrine cells--a new prognostic parameter in prostate cancer.

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