Doc Ophthalmol. 2009 Jun;118(3):205-16. Epub 2008 Dec 20.

Rod and S-cone driven ERG signals at high retinal illuminances.

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Department of Ophthalmology, University Hospital Erlangen-Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany. jan.kremers@uk-erlangen.de

Abstract

The purpose of the present study was to investigate whether L- and M-cone driven responses can be influenced by concomitant modulation in the rods or the S-cones. In addition, it was studied whether a change in the state of adaptation in L- or M-cones can have a different influence on ERG data when simultaneously the mean number of photoisomerizations in either rods or S-cones is altered. It was found that rods and/or S-cones cannot be neglected when measuring L- or M-cone driven ERGs.

PMID:: 19101744; [PubMed - indexed for MEDLINE]

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