Bioorg Khim. 2008 Nov-Dec;34(6):747-53.

[Identification of proteins in complexes with alpha-latrotoxin receptors].

[Article in Russian]

Serova OV, Popova NV, Deev IE, Petrenko AG.

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Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, Moscow, 117997 Russia.

Abstract

A thorough analysis of proteins capable of interacting with presynaptic receptors of alpha-latrotoxin was carried out. The protein components of receptor complexes were isolated from rat brain membranes by affinity chromatography on immobilized alpha-latrotoxin and antibodies to the cytoplasmic moiety of the calcium-independent receptor of alpha-latrotoxin (CIRL) followed by analysis by mass spectrometry. Several proteins were identified, with structural proteins, intracellular signal proteins, and proteins involved in the endocytosis and transport of synaptic vesicles being among them.

PMID:: 19088747; [PubMed - indexed for MEDLINE]

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Presynaptic alpha-latrotoxin receptor components interact with protein p65 of synaptic vesicle membranes. [Biomed Sci. 1991]
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Cited by 2 PubMed Central articles

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