Send to:

Choose Destination
See comment in PubMed Commons below
Vet J. 2009 Sep;181(3):211-20. doi: 10.1016/j.tvjl.2008.10.016. Epub 2008 Dec 11.

Animal models of henipavirus infection: a review.

Author information

  • 1National Centre for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, 1015 Arlington St., MB, Canada R3E 3M4.


Hendra virus (HeV) and Nipah virus (NiV) form a separate genus Henipavirus within the family Paramyxoviridae, and are classified as biosafety level four pathogens due to their high case fatality rate following human infection and because of the lack of effective vaccines or therapy. Both viruses emerged from their natural reservoir during the last decade of the 20th century, causing severe disease in humans, horses and swine, and infecting a number of other mammalian species. The current review summarises current published data relating to experimental infection of small and large animals, including the natural reservoir species, the Pteropus bat, with HeV or NiV. Susceptibility to infection and virus distribution in the individual species is discussed, along with the pathogenesis, pathological changes, and potential routes of transmission.

[PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Other Literature Sources

PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk