Abstract
Cucurbituril-based nanoparticles (CB[6]NPs) serve as new efficient vehicles for delivery of hydrophobic drugs, which have unique features including (1) a high drug loading capacity and efficiency, (2) noncovalently tunable surfaces, (3) efficient delivery of hydrophobic drugs into a cancer cell by receptor-mediated endocytosis, and (4) facile release of drugs into cytoplasm, which enhances the pharmaceutical effects of the drugs.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Coloring Agents
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Cytoplasm / drug effects
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Cytoplasm / metabolism
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Drug Delivery Systems*
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HeLa Cells
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Humans
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Macrocyclic Compounds / chemistry
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Microscopy, Confocal
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Nanoparticles / chemistry*
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Oxazines
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Particle Size
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Pharmaceutical Preparations / chemistry*
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Pharmaceutical Vehicles / chemistry*
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Photochemistry
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Solubility
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Water
Substances
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Coloring Agents
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Macrocyclic Compounds
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Oxazines
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Pharmaceutical Preparations
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Pharmaceutical Vehicles
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cucurbit(n)uril
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Water
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nile red