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Tetrahedron Lett. 2008 May 5;49(19):3045-3048.

Rational Design of a Fluorescent Hydrogen Peroxide Probe Based on the Umbelliferone Fluorophore.

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  • 1Department of Chemistry and Center for Biotechnology and Drug Design, Georgia State University, Atlanta, GA 30302-4098, USA.

Abstract

In this study, we report a novel water-soluble umbelliferone-based fluorescent probe for hydrogen peroxide. This probe shows very large increases (up to 100 fold) in fluorescent intensity upon reaction with hydrogen peroxide, and good selectivity over other reactive oxygen species (ROS).

PMID:
19081820
[PubMed]
PMCID:
PMC2490821
Free PMC Article
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