A global network for investigating the genomic epidemiology of malaria.

Achidi EA, Agbenyega T, Allen S, Amodu O, Bojang K, Conway D, Corran P, Deloukas P, Djimde A, Dolo A, Doumbo O, Drakeley C, Duffy P, Dunstan S, Evans J, Farrar J, Fernando D, Tran TH, Horstmann R, Ibrahim M, Karunaweera N, Kokwaro G, Koram K, Kwiatkowski D, Lemnge M, Makani J, Marsh K, Michon P, Modiano D, Molyneux ME, Mueller I, Mutabingwa T, Parker M, Peshu N, Plowe C, Puijalon O, Ragoussis J, Reeder J, Reyburn H, Riley E, Rogers J, Sakuntabhai A, Singhasivanon P, Sirima S, Sirugo G, Tall A, Taylor T, Thera M, Troye-Blomberg M, Williams T, Wilson M, Amenga-Etego L, Apinjoh TO, Bougouma E, Dewasurendra R, Diakite M, Enimil A, Hussein A, Ishengoma D, Jallow M, Lin E, Ly A, Mangano VD, Manjurano A, Manning L, Ndila CM, Nyirongo V, Oluoch T, Nguyen TN, Suriyaphol P, Toure O, Rockett KA, Vanderwal A, Clark T, Parker M, Wrigley R, Kwiatkowski D, Alcock D, Auburn S, Barnwell D, Bull S, Campino S, deVries J, Elzein A, Evans J, Fitzpatrick K, Ghansah A, Green A, Hart L, Hilton E, Hubbart C, Hughes C, Jeffreys AE, Kivinen K, MacInnis B, Manske M, Maslen G, McCreight M, Mendy A, Moyes C, Nyika A, Potter C, Risley P, Rowlands K, SanJoaquin M, Small K, Somaskantharajah E, Stevens M, Teo Y, Watson R, Agbenyega T, Carucci D, Cook K, Doyle A, Duombo O, Farrar J, Gottlieb M, Marsh K, Puijalon O, Taylor T, Kwiatkowski D.

The University of Buea, PO Box 63, Buea, South West Province, Cameroon.

Large-scale studies of genomic variation could assist efforts to eliminate malaria. But there are scientific, ethical and practical challenges to carrying out such studies in developing countries, where the burden of disease is greatest. The Malaria Genomic Epidemiology Network (MalariaGEN) is now working to overcome these obstacles, using a consortial approach that brings together researchers from 21 countries.

PMID: 19079050 [PubMed - indexed for MEDLINE]