Oral Dis. 2008 Oct;14(7):582-90.

Biofilm lifestyle of Candida: a mini review.

Source

Oral Bio-Sciences, Faculty of Dentistry, The University of Hong Kong, Hong Kong.

Abstract

Candida is the major fungal pathogen of humans causing a variety of afflictions ranging from superficial mucosal diseases to deep seated mycoses. Biofilm formation is a major virulence factor in the pathogenicity of Candida, and Candida biofilms are difficult to eradicate especially because of their very high antifungal resistance. Consequently, research into the pathogenicity of Candida has focused on the prevention and management of biofilm development, their architecture, and antifungal resistance. Although studies have shed some light, molecular mechanisms that govern biofilm formation and pathogenicity still await full clarification. This review outlines the key features of what is currently known of Candida biofilm development, regulation and antifungal resistance and, their proteomics.

PMID:: 19076549; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

COS Scholar Universe

Supplemental Content

Save items

Related citations in PubMed

Review Candida biofilms: antifungal resistance and emerging therapeutic options. [Curr Opin Investig Drugs. 2004]
Review Candida biofilms: antifungal resistance and emerging therapeutic options.
Kuhn DM, Ghannoum MA. Curr Opin Investig Drugs. 2004 Feb; 5(2):186-97.
Review Biofilms and their role in the resistance of pathogenic Candida to antifungal agents. [Curr Drug Targets. 2006]
Review Biofilms and their role in the resistance of pathogenic Candida to antifungal agents.
d'Enfert C. Curr Drug Targets. 2006 Apr; 7(4):465-70.
Review Community lifestyle of Candida in mixed biofilms: a mini review. [Mycoses. 2009]
Review Community lifestyle of Candida in mixed biofilms: a mini review.
Thein ZM, Seneviratne CJ, Samaranayake YH, Samaranayake LP. Mycoses. 2009 Nov; 52(6):467-75. Epub 2009 May 27.
Review Candida biofilm resistance. [Drug Resist Updat. 2004]
Review Candida biofilm resistance.
Mukherjee PK, Chandra J. Drug Resist Updat. 2004 Aug-Oct; 7(4-5):301-9.
Cell density and cell aging as factors modulating antifungal resistance of Candida albicans biofilms. [Antimicrob Agents Chemother. 2...]
Cell density and cell aging as factors modulating antifungal resistance of Candida albicans biofilms.
Seneviratne CJ, Jin LJ, Samaranayake YH, Samaranayake LP. Antimicrob Agents Chemother. 2008 Sep; 52(9):3259-66. Epub 2008 Jul 14.

See reviews... See all...

Cited by 5 PubMed Central articles

Conserved and divergent roles of Bcr1 and CFEM proteins in Candida parapsilosis and Candida albicans. [PLoS One. 2011]
Conserved and divergent roles of Bcr1 and CFEM proteins in Candida parapsilosis and Candida albicans.
Ding C, Vidanes GM, Maguire SL, Guida A, Synnott JM, Andes DR, Butler G. PLoS One. 2011; 6(12):e28151. Epub 2011 Dec 1.
Global screening of potential Candida albicans biofilm-related transcription factors via network comparison. [BMC Bioinformatics. 2010]
Global screening of potential Candida albicans biofilm-related transcription factors via network comparison.
Wang YC, Lan CY, Hsieh WP, Murillo LA, Agabian N, Chen BS. BMC Bioinformatics. 2010 Jan 26; 11:53. Epub 2010 Jan 26.
Characterization of mucosal Candida albicans biofilms. [PLoS One. 2009]
Characterization of mucosal Candida albicans biofilms.
Dongari-Bagtzoglou A, Kashleva H, Dwivedi P, Diaz P, Vasilakos J. PLoS One. 2009 Nov 24; 4(11):e7967. Epub 2009 Nov 24.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Biofilm lifestyle of Candida: a mini review.
Biofilm lifestyle of Candida: a mini review.
Oral Dis. 2008 Oct ;14(7):582-90.

PubMed
Clinical relevance of sensitization to lupine in peanut-sensitized adults.
Clinical relevance of sensitization to lupine in peanut-sensitized adults.
Allergy. 2009 Apr ;64(4):549-55. Epub 2008 Dec 4 .

PubMed
Impact of peanut allergy on quality of life, stress and anxiety in the family.
Impact of peanut allergy on quality of life, stress and anxiety in the family.
Allergy. 2009 Mar ;64(3):461-8. Epub 2008 Dec 4 .

PubMed
A sex difference in mental rotation in young infants.
A sex difference in mental rotation in young infants.
Psychol Sci. 2008 Nov ;19(11):1067-70.

PubMed
The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodeg...
The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration.
Ann N Y Acad Sci. 2008 Dec ;1147:61-9.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: