Recent Pat Biotechnol. 2007;1(2):151-66.

Plasmid DNA manufacturing technology.

Source

Nature Technology Corporation, Lincoln, NE 68521, USA. acarnes@natx.com

Abstract

Today, plasmid DNA is becoming increasingly important as the next generation of biotechnology products (gene medicines and DNA vaccines) make their way into clinical trials, and eventually into the pharmaceutical marketplace. This review summarizes recent patents and patent applications relating to plasmid manufacturing, in the context of a comprehensive description of the plasmid manufacturing intellectual property landscape. Strategies for plasmid manufacturers to develop or in-license key plasmid manufacturing technologies are described with the endpoint of efficiently producing kg quantities of plasmid DNA of a quality that meets anticipated European and FDA quality specifications for commercial plasmid products.

PMID:: 19075838; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Supplemental Content

Icon for Bentham Science Publishers Ltd.

Save items

Related citations in PubMed

Review Upstream processing of plasmid DNA for vaccine and gene therapy applications. [Recent Pat Biotechnol. 2008]
Review Upstream processing of plasmid DNA for vaccine and gene therapy applications.
Tejeda-Mansir A, Montesinos RM. Recent Pat Biotechnol. 2008; 2(3):156-72.
Review Plasmid DNA for pharmaceutical applications. [Dev Biol (Basel). 2000]
Review Plasmid DNA for pharmaceutical applications.
Schleef M, Schmidt T, Flaschel E. Dev Biol (Basel). 2000; 104:25-31.
Generic plasmid DNA production platform incorporating low metabolic burden seed-stock and fed-batch fermentation processes. [Biotechnol Bioeng. 2009]
Generic plasmid DNA production platform incorporating low metabolic burden seed-stock and fed-batch fermentation processes.
Williams JA, Luke J, Langtry S, Anderson S, Hodgson CP, Carnes AE. Biotechnol Bioeng. 2009 Aug 15; 103(6):1129-43.
The intellectual property landscape in the field of plasmid-based gene therapy. [J Drug Target. 2000]
The intellectual property landscape in the field of plasmid-based gene therapy.
Fons MP. J Drug Target. 2000; 7(6):407-11.
Review A simple method for the production of plasmid DNA in bioreactors. [Methods Mol Med. 2006]
Review A simple method for the production of plasmid DNA in bioreactors.
Listner K, Bentley LK, Chartrain M. Methods Mol Med. 2006; 127:295-309.

See reviews... See all...

Cited by 2 PubMed Central articles

Polyclonal antibody cocktails generated using DNA vaccine technology protect in murine models of orthopoxvirus disease. [Virol J. 2011]
Polyclonal antibody cocktails generated using DNA vaccine technology protect in murine models of orthopoxvirus disease.
Golden JW, Zaitseva M, Kapnick S, Fisher RW, Mikolajczyk MG, Ballantyne J, Golding H, Hooper JW. Virol J. 2011 Sep 20; 8:441. Epub 2011 Sep 20.
Generic plasmid DNA production platform incorporating low metabolic burden seed-stock and fed-batch fermentation processes. [Biotechnol Bioeng. 2009]
Generic plasmid DNA production platform incorporating low metabolic burden seed-stock and fed-batch fermentation processes.
Williams JA, Luke J, Langtry S, Anderson S, Hodgson CP, Carnes AE. Biotechnol Bioeng. 2009 Aug 15; 103(6):1129-43.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Plasmid DNA manufacturing technology.
Plasmid DNA manufacturing technology.
Recent Pat Biotechnol. 2007 ;1(2):151-66.

PubMed
Nutraceuticals, nutritional therapy, phytonutrients, and phytotherapy for improv...
Nutraceuticals, nutritional therapy, phytonutrients, and phytotherapy for improvement of human health: a perspective on plant biotechnology application.
Recent Pat Biotechnol. 2007 ;1(1):75-97.

PubMed
Recent developments in antitubercular drugs.
Recent developments in antitubercular drugs.
Mini Rev Med Chem. 2008 Dec ;8(14):1441-51.

PubMed
SRC as a therapeutic target in breast cancer.
SRC as a therapeutic target in breast cancer.
Endocr Metab Immune Disord Drug Targets. 2008 Dec ;8(4):273-8.

PubMed
Biological and pharmacological activities of carvacrol and carvacrol bearing ess...
Biological and pharmacological activities of carvacrol and carvacrol bearing essential oils.
Curr Pharm Des. 2008 ;14(29):3106-19.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Plasmid DNA manufacturing technology.

Source

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Supplemental Content

Save items

Related citations in PubMed

Cited by 2 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information