Mini Rev Med Chem. 2008 Dec;8(14):1441-51.

Recent developments in antitubercular drugs.

Source

Type V/11, NIPER Campus, Sector-67, SAS Nagar (Mohali)- 160062, Punjab, India. pahirrao11@gmail.com

Abstract

This review article describes the current TB drugs, their merits and demerits as well as the new promising anti-TB agents such as diarylquinolines, oxazolidinones and nitroimdiazoles. It also includes the future development of new antitubercular agents according to the potential drug targets of Mycobacterium tuberculosis and structure-activity relationship studies on important anti-TB drugs.

PMID:: 19075802; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Review

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Supplemental Content

Icon for Bentham Science Publishers Ltd.

Save items

Related citations in PubMed

Review Structural biology and biochemistry of cytochrome P450 systems in Mycobacterium tuberculosis. [Drug Metab Rev. 2008]
Review Structural biology and biochemistry of cytochrome P450 systems in Mycobacterium tuberculosis.
McLean KJ, Munro AW. Drug Metab Rev. 2008; 40(3):427-46.
Review Current status of some antituberculosis drugs and the development of new antituberculous agents with special reference to their in vitro and in vivo antimicrobial activities. [Curr Pharm Des. 2006]
Review Current status of some antituberculosis drugs and the development of new antituberculous agents with special reference to their in vitro and in vivo antimicrobial activities.
Tomioka H. Curr Pharm Des. 2006; 12(31):4047-70.
Review 5-tert-butyl-N-pyrazol-4-yl-4,5,6,7-tetrahydrobenzo[d]isoxazole-3-carboxamide derivatives as novel potent inhibitors of Mycobacterium tuberculosis pantothenate synthetase: initiating a quest for new antitubercular drugs. [J Med Chem. 2008]
Review 5-tert-butyl-N-pyrazol-4-yl-4,5,6,7-tetrahydrobenzo[d]isoxazole-3-carboxamide derivatives as novel potent inhibitors of Mycobacterium tuberculosis pantothenate synthetase: initiating a quest for new antitubercular drugs.
Velaparthi S, Brunsteiner M, Uddin R, Wan B, Franzblau SG, Petukhov PA. J Med Chem. 2008 Apr 10; 51(7):1999-2002. Epub 2008 Mar 13.
Diarylquinolines, synthesis pathways and quantitative structure--activity relationship studies leading to the discovery of TMC207. [Future Med Chem. 2011]
Diarylquinolines, synthesis pathways and quantitative structure--activity relationship studies leading to the discovery of TMC207.
Guillemont J, Meyer C, Poncelet A, Bourdrez X, Andries K. Future Med Chem. 2011 Sep; 3(11):1345-60.
A new family of inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase. [Nucleosides Nucleotides Nuclei...]
A new family of inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
Gasse C, Huteau V, Douguet D, Munier-Lehmann H, Pochet S. Nucleosides Nucleotides Nucleic Acids. 2007; 26(8-9):1057-61.

See reviews... See all...

Recent activity

Clear Turn Off Turn On

Recent developments in antitubercular drugs.
Recent developments in antitubercular drugs.
Mini Rev Med Chem. 2008 Dec ;8(14):1441-51.

PubMed
SRC as a therapeutic target in breast cancer.
SRC as a therapeutic target in breast cancer.
Endocr Metab Immune Disord Drug Targets. 2008 Dec ;8(4):273-8.

PubMed
Biological and pharmacological activities of carvacrol and carvacrol bearing ess...
Biological and pharmacological activities of carvacrol and carvacrol bearing essential oils.
Curr Pharm Des. 2008 ;14(29):3106-19.

PubMed
Molecular imaging of brain tumors personal experience and review of the literatu...
Molecular imaging of brain tumors personal experience and review of the literature.
Curr Mol Med. 2008 Dec ;8(8):711-26.

PubMed
Two years treatment with almitrine bismesylate in patients with hypoxic chronic ...
Two years treatment with almitrine bismesylate in patients with hypoxic chronic obstructive airways disease.
Eur Respir J. 1991 Mar ;4(3):308-10.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: