Format

Send to:

Choose Destination
See comment in PubMed Commons below
Ann Intern Med. 2008 Dec 16;149(12):889-97.

Systematic reviews of diagnostic test accuracy.

Author information

  • 1Dutch Cochrane Centre and Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.

Abstract

More and more systematic reviews of diagnostic test accuracy studies are being published, but they can be methodologically challenging. In this paper, the authors present some of the recent developments in the methodology for conducting systematic reviews of diagnostic test accuracy studies. Restrictive electronic search filters are discouraged, as is the use of summary quality scores. Methods for meta-analysis should take into account the paired nature of the estimates and their dependence on threshold. Authors of these reviews are advised to use the hierarchical summary receiver-operating characteristic or the bivariate model for the data analysis. Challenges that remain are the poor reporting of original diagnostic test accuracy studies and difficulties with the interpretation of the results of diagnostic test accuracy research.

Comment in

PMID:
19075208
[PubMed - indexed for MEDLINE]
PMCID:
PMC2956514
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Silverchair Information Systems Icon for PubMed Central
    Loading ...
    Write to the Help Desk