Send to:

Choose Destination
See comment in PubMed Commons below
J Clin Pathol. 2008 Dec;61(12):1261-75. doi: 10.1136/jcp.2008.055244.

The placenta in preterm birth.

Author information

  • 1The University of Alabama at Birmingham, Birmingham, AL 35249-7331, USA.


Rates of preterm birth range from 5% to 13% of deliveries in developed countries. About two-thirds of preterm deliveries are due to spontaneous onset of preterm labour or preterm premature rupture of membranes. Approximately one-third follow induction of labour or caesarean section performed for maternal or fetal indications such as preeclampsia, haemorrhage, non-reassuring fetal heart rate or intrauterine growth restriction. Thus, pathologists are frequently called on to evaluate preterm placentas, to determine the cause of the spontaneous preterm birth and/or correlate placental findings with the clinical history. This review provides pathologists with an overview of the recent clinical research in the pathogenesis of preterm birth and relates these to the correlative placental pathologies of the major causes of spontaneous preterm birth. A brief summary of the placental gross and histopathological findings in indicated preterm birth is also included.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Write to the Help Desk