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Neurosurgery. 2008 Dec;63(6):E1204; discussion E1204. doi: 10.1227/01.NEU.0000335781.27643.5B.

Increase of frequency in deep brain stimulation relieves apraxia of eyelid opening in patients with Parkinson's disease: case report.

Author information

  • 1Department of Neurology, University of Leipzig, Leipzig, Germany. KarlStrecker@gmx.de

Abstract

OBJECTIVE:

Deep brain stimulation (DBS) of the subthalamic nucleus is an effective treatment in advanced stages of Parkinson's disease. However, approximately 5% of patients might develop apraxia of eyelid opening after DBS of the subthalamic nucleus. We provide data on a new noninvasive treatment approach to this adverse event.

CLINICAL PRESENTATION:

We report 2 patients who acquired apraxia of eyelid opening after DBS. This adverse event was relieved by changing the stimulation parameters.

INTERVENTION:

The stimulation frequency was increased from 100 Hz to 180 Hz in 1 patient and 160 Hz in the other, resulting in a total relief of symptoms.

CONCLUSION:

Increasing stimulation frequency may be beneficial in apraxia of eyelid opening acquired after DBS of the subthalamic nucleus.

PMID:
19057285
[PubMed - indexed for MEDLINE]
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