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Cutis. 2008 Oct;82(4):242-8.

A "hyperextensive" review of Ehlers-Danlos syndrome.

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  • 1Dermatology and Pediatrics, New Jersey Medical School, Newark 07103-2714, USA. neil.fernandes@uphs.upenn.edu


Ehlers-Danlos syndrome (EDS) is a heterogeneous group of connective tissue disorders characterized by hyperextensibility, delayed wound healing, joint hypermobility, thin skin, easy bruising, tissue fragility, "cigarette-paper" scarring over bony prominences, mitral valve prolapse, and other findings. There are 6 main types of EDS. Regardless of presentation as a chief concern or an incidental finding, physicians should be aware that the prominent skin findings of EDS are cutaneous signs of an important systemic disorder.

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