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Cancer Res. 2008 Dec 1;68(23):9567-9. doi: 10.1158/0008-5472.CAN-08-3008.

Fetal microchimerism and cancer.

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  • 1Lankenau Institute for Medical Research, Wynnewood, Pennsylvania 19096, USA.


The persistence of fetal stem cells with multilineage potential in women who have been pregnant, a phenomenon known as fetal microchimerism, is emerging as a potential contributing factor in certain diseases, including cancer. For example, fetal microchimerism has been implicated in autoimmune disease, wound healing, and cancer. Studies of this phenomenon may provide a novel perspective on cancer in women, including in breast, ovarian, and lung cancers.

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