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Nat Cell Biol. 2008 Dec;10(12):1383-4. doi: 10.1038/ncb1208-1383.

A TRP channel-steroid marriage.

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  • 1Department of Molecular Cell Biology, Laboratory of Ion Channel Research, KU Leuven, Campus Gasthuisberg, Herestraat 49, bus 802, B-3000 Leuven, Belgium. bernd.nilius@med.kuleuven.be

Abstract

A surprising functional association between TRPM3, a mysterious member of the family of transient receptor potential (TRP) cation channels, and the sulphated version of pregnenolone, 'mother' of all steroid hormones, has been identified.

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