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    Vaccine. 2009 Jan 29;27(5):718-25. Epub 2008 Nov 27.

    Cost-effectiveness analysis of behavioral interventions to improve vaccination compliance in homeless adults.

    Greengold B, Nyamathi A, Kominski G, Wiley D, Lewis MA, Hodge F, Singer M, Spiegel B.

    University of California, Los Angeles, School of Nursing, Box 956917, Los Angeles, CA 90095-6917, USA.

    AIMS: To estimate the cost-effectiveness of three behavioral interventions provided to enhance hepatitis A virus (HAV) and hepatitis B virus (HBV) joint vaccination (HAV/HBV) compliance among homeless persons living in Los Angeles County. SCOPE: A cost-effectiveness analysis (CEA) based on data from a randomized trial where the costs and compliance data from the trial are incorporated into two Markov models, simulating the natural history of acute and chronic hepatitis infection, following HAV/HBV vaccination. CONCLUSIONS: Reductions in HBV-related disease is cost-effective to society and is associated with substantial improvements in quality of life.

    PMID: 19041351 [PubMed - indexed for MEDLINE]

    PMCID: 2772200

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